Start time, team news, and lineups for Barcelona vs. Inter in the UEFA Champions League

Barcelona vs. Inter;

Barcelona hosts Italian giants Inter Milan in the opening leg of their UEFA Champions League semifinal.

With eight UEFA Champions League titles between them, Barcelona and Inter Milan begin their battle for the right to enter another final when they square off in the opening leg of their semifinal showdown on Wednesday night.

Barcelona, who have only lost a single match in 2025, will host Inter at the Olympic Stadium, with the two-leg series then moving to Northern Italy next Tuesday, May 6 for the return fixture at the famous San Siro venue.

Here is all to know before the semifinal opener between two of Europe’s football superclubs:

When did Barcelona and Inter Milan last play each other in the Champions League?

The most recent encounter between both teams took place in Barcelona’s Nou Camp in Group C on October 12, 2022.

Ousmane Dembele of Barcelona, who  scored the game-winning goal for PSG against Arsenal in the other Champions League semifinal on Tuesday, gave the Catalans the lead in the first half of the match. A wild five-goal second half followed, with Robert Lewandowski scoring the equalizer in stoppage time to split the points. The teams ended up drawing 3-3.

Who did Barcelona and Inter Milan defeat to reach the semifinal stage?

Borussia Dortmund, the runner-up in the UEFA Champions League the previous year, lost to Barcelona 5-3 on aggregate in their two-leg quarterfinal.

Possible lineups:

Barcelona possible starting XI: Szczesny; Kounde, Cubarsi, Martinez, Martin; De Jong, Pedri; Yamal, Olmo, Raphinha; Torres

Inter Milan possible starting XI: Sommer; De Vrij, Acerbi, Augusto; Darmian, Frattesi, Calhanoglu, Barella, Dimarco; Martinez, Thuram.